How long does it take for Lexapro to work?.SSRI’s vs SNRI’s - What's the difference between them?. The likelihood of interactions with other drugs (such as monoamine oxidase inhibitors, pimozide, tramadol, St John’s wort) is similar.Both are prescription medicines, and neither is a controlled drug.Both are branded drugs however, generics are available for each drug which makes costs similar.Both have been associated with withdrawal symptoms when discontinued.Side effects, such as headache, nausea and vomiting, nervousness and anxiousness, dizziness, sexual problems (eg, erectile dysfunction), tremor, and weight gain (although this tends to be less than with other antidepressants) or weight loss are common to both Lexapro and Zoloft.SSRIs increase levels of serotonin in the nerve synapse and this has been associated with a reduction in depressive symptoms They both work by preventing the reuptake of serotonin, a chemical in the brain that acts as a messenger between nerve cells.Lexapro was FDA approved in 2002 and Zoloft was FDA approved in 1991.īecause both drugs are SSRIs, they have many similarities, such as:.There is some evidence that Lexapro may be more effective than other SSRIs, including Zoloft, in the treatment of depression.There are some differences in their side effects with Lexapro being more likely to cause sleep problems and taste disturbances, and Zoloft is more likely to cause skin rash or diarrhea.Zoloft is also FDA approved to treat OCD (obsessive-compulsive disorder), panic disorder, PTSD (post-traumatic stress disorder), social phobia, and premenstrual dysphoric disorder (PDD).Lexapro is a branded version of escitalopram and Zoloft is a branded version of sertraline.The main differences between Lexapro and Zoloft are: Both are available in tablet and liquid forms. Both Lexapro and Zoloft belong to the class of medicines called selective serotonin reuptake inhibitors (SSRIs) and are both FDA approved to treat anxiety and depression.
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